Radiation oncology

 

 

Publication Record

 

Ang, K.K., A. Trotti, A. S. Garden, R. L. Foote, W. H. Morrison, F. B. Geara, W. Klotch, L. J. Peters, and H. Goepfert. 2001. Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer. Int. J. Radiat. Oncol. Biol. Phys.51:571–8.

        

Garden, A. S., B. S. Glisson, K. K. Ang, W. H. Morrison, S. M. Lippman, R. M. Byers, F. Geara, G. L. Clayman, D. M. Shin, D. L. Callender, F. R. Khuri, H. Goepfert, W. K. Hong, and L. J. Peters. 1999.  Phase I/II trial of radiation with chemotherapy "boost" for advanced squamous cell carcinomas of the head and neck: Toxicities and responses. J Clin Oncol 17 (8):2390.

        

Geara, F. 1999. Radiotherapy for gastrointestinal lymphomas: indications and techniques. Cancer Radiother 3 (2):141–148.

        

Meyers, C., F. B. Geara, P. F. Wong, and W. H. Morrison. 2000. Neurocognitive effects of therapeutic irradiation for base of skull tumors.  Int J Radiat Oncol Biol Phys 46:51–5.

        

Muwakkit, S., F. Geara, B. Nabbout, R. Farah, N. S. Shabb, T. Hajjar, and M. Khogali. 1999. Treatment of pediatric hodgkin’s disease with chemotherapy alone or combined modality therapy. Radiat Oncol Invest 7 (6):365–373.

        

Liebross, R.H., A. Pollack, S. P. Lankford, G. K. Zagars, A. C. von Eschenbach, and F. B. Geara. 1999.  Transrectal ultrasound for staging prostate carcinoma prior to radiation therapy: An evaluation based on disease outcome. Cancer 85 (7):1577–1585.

        

 

 

Abstracts, Conferences, and Proceedings

 

Geara F. June 1999. Definitive and Adjunctive Therapies for Nasopharyngeal Cancer.  Department of Radiation Oncology, St. Luc University Hospital, Universite Catholique de Louvain, June 1999, Brussels, Belgium.

    

 

Ang, K.K., A. Trotti, A. S. Garden, R. L. Foote, W. H. Morrison, F. B. Geara, W. Klotch, L. J. Peters, and H. Goepfert. October 1999. Impact of risk factors and total time of surgery plus radiotherapy on the outcome of patients with advanced head and neck cancer. American Society for Therapeutic Radiology and Oncology (ASTRO), San Antonio, USA.

 

Hourani, M., G. Zaytoun, D. Hammoud, F. B. Geara, and A. M. Al-Kutoubi. March 2000. Use of sestamibi SPECT in detection of recurrent laryngeal cancer. Eurpoean Society of Nuclear Medicine, Annual  Meeting, Vienna, March, 2000.

 

Geara, F. B., E. Nasr, S. L. Tucker, G. Zaytoun, E. Brihi, Z. Salem, N. Saghir, A. Shamseddine, and P. Issa.  September 2000. Nasopharyngeal cancer (NPC) in the Middle East: Experience of the American University of Beirut Medical Center. European Society for Therapeutic Radiology and Oncology (ESTRO), Istanbul.

 

Geara, F. B., E. Nasr, S. L. Tucker, K. Bikhazi, J. Abbas, Z. Salem, N. ElSaghir, A. Shamseddine, and P. Issa. Januray 2001. Results of adjuvant radiotherapy alone and combined modality therapy for high risk breast cancer patients with 10 or more positive axillary lymphnodes. International Congress of Radiation oncology (ICRO), Melbourne, Australia.

 

El Saghir, N., F. B. Geara, A. Tawil, A. Taher, Z. Salem, A. Khalil, and M. Seoud. May 2001. Age distribution of breast cancer in Lebanon: Analysis of 2282 cases from the American University of Beirut Medical Center. The American Society of Clinical Oncology Annual Meeting, San Francisco, USA.

 

Khauli, R. B., M. Bulbul, W. Wazzan, A. Hijaz, R. Nasr, F. Freiha, M. Haddad, F. Geara, and A. Tawil. June 2001. Radical retropubic prostatectomy: Association of conventional clinical parameters and PSA indexes in extraprostatic disease and micrometastasis. The American Urologic Association Anaheim, California, USA.

 

Geara, F. February 2000. Current therapy of nasopharyngeal cancer.  Department of Oncology, King Faisal Hospital and Research Center, Saudi Arabia.

 

———. April 2000. Combined hormonal ablation and radiation therapy for prostate cancer. April 2000. The Lebanese Society of Urology, Beirut, Lebanon.

 

———. January 2001. Recent advances in non-surgical therapy of laryngeal cancer. The Lebanese Society of HN surgery annual meeting, Beirut, Lebanon.

    

———. February 2001. Radiation therapy for mesothelioma. The Lebanese Society of Medical oncology continued medical education program. Beirut, Lebanon.

   

 

 

Research Project

 

Accelerated versus conventional radiation therapy for head and neck cancers using six versus five fractions per week

 

The aim of this international multi-institutional study is to determine the possible therapeutic gain obtained by reducing the overall treatment time in the radiation treatment of patients with head and neck cancer who are candidates for primary external radiotherapy alone. The protocol seeks to establish the importance of 5 vs. 6 weekly radiotherapy fractions of 2 Gy given to the same total dose.

 

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The study design is a stratified, balanced, and randomized study (phase III) of patients with Stage I-IV squamous cell carcinoma of the pharynx (except nasopharynx­ and stage I glottic carcinoma), larynx and oral cavity. The study randomizes to 5 versus 6 fractions per week­ and the stratification is based on the following parameters: - tumor stage; - tumor site; - histological differentiation; and institution. Endpoints of the study include crude survival, primary tumor control in T and N position (primary endpoint), disease free survival, and treatment related acute and late morbidity. Geara, F., and N. Fuleihan.

 

Supported by the International Atomic Energy Agency, Vienna, Austria