RESEARCH PROJECTS
The effect of estrogen on pigment production by melanocytes A
possible role for sex hormones in the pathogenesis of melasma has been
suggested because of its frequent association with pregnancy and oral contraceptives.
Estrogenic hormones are thought to enhance melanogenesis, but the mechanisms
by which they interact with the melanin system are still unclear. The purpose
of this project is to study the effect of sex hormones on melanocyte cell
function, and more specifically, on the synthesis of melanin, and to determine
whether melanogenesis is stimulated through the activation of protein kinase
C. N.G. Rubeiz, A.G. Kibbi, Sh. Zaynoun. (Supported by URB, LNCSR,
and MPP.)
Epidemiology of skin cancer at the American University of Beirut Medical Center—data from the tumor registry The
objective of this project is to study the epidemiology of skin cancer reported
to the Tumor Registry at the American University of Beirut Medical Center
between 1982 till present. The demographic data will be analyzed and risk
factors defined in an attempt to determine trends and to draw preventive
strategies against skin cancer in the country. To the best of our knowledge,
this study has been done in the country in the early seventies and since
then, no data has been published on this topic. N.G., Rubeiz, S.M. Salman.
The impact of different topical agents on the healing of wounds status-post medium depth chemical peeling. The
study was designed to assess and compare the effects of pre and/or post-treatment
of pig’s skin wounds with one or combinations of tretinoin, glycolic acid,
estrogen, amonium lactate and vitamin C. Preliminary results demonstrated
that tretinoin, glycolic acid, estrogen, and vitamin C exert their effects
on non-photodamaged and hormonally extragenital non-aged skin of pigs.
Pre-treatment with these agents produced variable qualitative morphological
changes related to epithelialization, fibroplasia, elastic fiber and ground
substance formation. S.M., Salman, A.G. Kibbi. (Supported by MPP.)
Choi, S.W.*, Sachs, D.*, Park, H.Y.*, Rubeiz, N.G., Gilchrest, B.A.*, Protein kinase C-a levels are inversely associated with growth rate in cultured human dermal fibroblast. Journal of Dermatological Science, 18, 54-63, 1998. Kibbi, A.G., Tannous, Z.S., Diseases caused by heat and cold. Clinics in Dermatology, 16 (1), 91-99, 1998. Malak, J., Hadi, U., Otic rosacea. Archives of Otolaryngology—Head and Neck Surgery, 125 (4), 479, 1999. Nuwayri-Salti, N., Matta, M., Shbaklo, Z., Lakkis, M., El-Jisr Kabbani, Z., Behavior in a mouse model of isolates of leishmania donovani sensu lato cultured from the blood of patients with chronic cutaneous lesions. American Journal of Tropical Medicine and Hygiene, 58, 710-714, 1998. Phillips, T.*, Salman, S.M., Rogers, G.*, Burn scar carcinoma, diagnosis and management. Journal of Dermatologic Surgery, 24 (5), 561-5, 1998. Salman, S.M., Rubeiz, N.G., Kibbi, A.G., Cutaneous leishmaniasis: clinical features and diagnosis. Clinics in Dermatology, 17, 291-296, 1999. Shamseddine, A.I., Khalil, A. M., Kibbi, A.G., Abu Nasr, T.A., Seoud, M. A.F., El Saghir, N.S., Granulocyte macrophage-colony stimulating factor for treatment of chemotherapy extravasation. European Journal of Gynecologic Oncology, 19, 479-481, 1998. Wolff,
K.*, Kibbi, A.G., Mihm, M.C., Jr.*, Basic pathologic reactions of the skin.
In Dermatology in General Medicine, ed. Freedberg, I., Eisen, A.Z.,
Wolff, K., Austen K.F., Goldsmith, L.A., Katz, S.I., and Fitzpatrick, T.B.,
41-55. New York: McGraw–Hill Companies, Inc., 1999.
ABTRACTS, PROCEEDINGS AND PRESENTATIONSEl
Saad Debahy, N., Newer modalities for the treatment of facial scars.
The 6th Congress of Pan Arab League of Dermatologists, Beirut,
Lebanon, 1998.
———,
Laser skin resurfacing. The Third Dermatology Update Conference,
Beirut, Lebanon, 1997.
El-Sayed F., Why should I patch test? The Third Dermatology Update Conference, Beirut, Lebanon, 1997. Kibbi, A.G., Genital warts: should we treat and how? The Third Dermatology Update Conference, Beirut, Lebanon, 1997. ———, Cutaneous necrotizing vasculitis: an update. The 4th GCC International conference of Dermatology and Venereology, Kuwait, 1997. ———, Vasculitis in children. The 6th International Symposium of Dermatology and Venereology, Al Khobar, Saudi Arabia, 1998. ———, How to write and publish in the Dermatosciences. The 6th International Symposium of Dermatology and Venereology, Al Khobar, Saudi Arabia, 1998. Matta, M., Treatment of analopecia with finasteride. The 6th Congress of Pan Arab League of Dermatologists, Beirut, Lebanon, 1998. ———, Skin manifestations of sports participation. The Third Dermatology Update Conference, Beirut, Lebanon, 1997. Rubeiz, N.G., Serious and life-threatening skin diseases. The Third Dermatology Update Conference, Beirut , Lebanon, 1997. ———, Herpes simplex virus (HSV) infection. First International Seminar on Aids and STD, Damascus, Syria, 1997. Rubeiz, N.G., Haj Ibrahim, H., Matta, M., Kibbi, A.G., Perifollicular elastolysis. The 56th Annual Meeting of the American Academy of Dermatology, Orlando, Florida, USA, 1998. Rubeiz, N.G., Kibbi, A.G., Acute hemorrhagic edema of infancy. The 57th Annual Meeting of the American Academy of Dermatology, New Orleans, Louisiana, USA, 1999. Rubeiz, N.G., Shbaklo, Z., Kibbi, A.G., Oral and genital langerhans cell histiocytosis. The 57th Annual Meeting of the American Academy of Dermatology, New Orleans, Louisiana, USA, 1999. Rubeiz, N.G., Tannir, D., Kibbi, A.G., Sweets’ syndrome: a review of 27 cases. The 55th Annual Meeting of the American Academy of Dermatology, San Francisco, USA, 1997. Salman, S.M., The impact of different topical agents on the healing of wounds s/p medium depth exfoliation. The 6th Congress of the Pan Arab League of Dermatology, Beirut, Lebanon, 1998. ———, Electrosurgical treatment of rhinophyma. The Third Dermatology Update Conference, Beirut, Lebanon, 1997. ———, Kaposi’s Sarcoma. First sexually transmitted disease. First International Seminar on Aids and STD, Damascus, Syria, 1997. Salman, S.M., Rubeiz, N.G., Awar, G., Kibbi, A.G., Malignant angioendotheliomatosis. The 56th Annual Meeting of the American Academy of Dermatology, Orlando, Florida, USA, 1998. Salman, S.M., Tannir, D., Rubeiz, N.G., Kibbi, A.G., Multiple winer pores: case report. The 56th Annual Meeting of the American Academy of Dermatology, Florida, USA, 1998. Shbaklo, Z., Profile of leprosy in Lebanon: epidemiology and clinical presentations. The 6th Congress of Pan Arab League of Dermatologists, Beirut, Lebanon, 1998. ———, Human papilloma viruses. The Third Dermatology Update Conference, Beirut, Lebanon, 1997. Zaynoun, Sh., The clinical differential diagnosis of solitary red nodules. The Third Dermatology Update Conference, Beirut, Lebanon, 1997. ———,
Photosensitization by psoralens in fig and garden parsley. The 6th
Congress of Pan Arab League of Dermatologists, Beirut, Lebanon, 1998.
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