Thesis and Publications by Users of the CRSL Equipment

Thesis Titles

 

 

July 2002

 

Thesis Title:             Effect of GJIC Modulation on JAK2/STATS in Mammary Cells in Vitro

Graduate's Name:    Ayman Mohammad Ismail

Department:             Biology

Advisor's Name :     Dr. Rabih Talhouk

Equipment Used:     X-ray film processor, and Fluorescence Microscope

 

May 2003 - June 2003

 

Thesis Title:               The Antimicrobial Effects of Components of the Oil of Lebanese Sage (Salvia Libanotica)

Graduate's Name:     Rodaina Omar Haidar

Department:             Biology

Advisor's Name:      Dr. Medhat Khattar

Equipment Used:      Fluorescence Microscope

 

Thesis Title:                 Isolation and Priliminary Characterisation of a New Temperature-Sensitive Allele of the NAD+ Ligase Gene (LIGA) in Escherichia Coli

Graduate's Name:     Hadi Mohamad Yassine

Department:                Biology

Advisor's Name:         Dr. Medhat Khattar

Equipment Used:        Fluorescence microscope

 

Thesis Title:                 Isolation and Characterisation of a Temperature-Sensitive Mutation in the 88-89 Minutes of the Escherichia Coli Chromosome

Graduate's Name:       Issmat Ibrahim Kassem

Department:                Biology

Advisor's Name:         Dr. Medhat Khattar

Equipment Used:        Fluorescence Microscope

 

Thesis Title:               Development of Serological Assays for Diagnosis of Cucurbit Yellow Stunting Disorder Virus using Molecular Techniques

Graduate's Name:     Hala Hourani

Department:              Agriculture

Advisor's Name:       Dr. Youssef Abou Jawdeh

Equipment Used:      Fluorescence Microscope, Gel Documentation System, Super Speed Centrifuge, Water Deionizer, and Distiller

 

Thesis Title:                Development of Molecular Techniques for Specific Identification of Almond and Tomato Phytoplasmas

Graduate's Name:     Shoaa El-Mehtar

Department:             Agriculture

Advisor's Name:      Dr. Youssef Abou Jawdeh

Equipment Used:      X-ray Film Developer, Water Deionizer, and Distiller

 

Thesis Title:             Development of Molecular Biology Techniques for the Diagnosis of Frunus Necrotic Ringspot Virus

Graduate's Name:     Hadia Kawtharani

Department:             Agriculture

Advisor's Name:       Dr. Youssef Abou Jawdeh

Equipment Used:      Super Speed Centrifuge, Water Deionizer, and Distiller

 

Thesis Title:             Morphological and Biomedical Alterations of Intestinal Tissues in Experimental Inflammatory Bowel Disease

Graduate's Name:     Naim Khoury

Department:             Medical School

Advisor's Name:       Dr. Abdo Jurjus

Equipment Used:      Fluorescence Microscope

 

July 2003 - September 2003

 

Thesis Title:             Molecular Mechanisms of Antineoplastic Effects by Thymoquinone in Neoplastic Keratinocytes

Graduate's Name:     Wassim Gergy Abou Kheir

Department:              Biology

Advisor's Name:       Dr. Hala Muhtasib

Equipment Used:       Flowcytometer, Fluorescence Microscope

 

Thesis Title:             Mechanisims of HPR-Induced Cell Death in HTLV-1 Transformed

Graduate's Name:    Humam Nabil Kabbara

Department:             Biology

Advisor's Name:      Dr. Nadine Darwiche

Equipment Used:     Flowcytometer, and Fluorescence Microscope

 

Thesis Title:             Characterisation of Potential Anti-Inflammatory Bioactivities in Selected Indigenous Medicinal Plants of Lebanon

Graduates Name:     Wassim El-Jouni

Department:             Biology

Advisor's Name:     Dr. Rabih Talhouk

Equipment Used:     Fluorescence Microscope, X-Ray Film Developer

 

Thesis Title:             The Gap Junction Protein Complex: Role in Mammary Epithelial Cell Differentiation

Graduate's Name:     Ralda Nehme

Department:             Biology

Advisor's Name:      Dr. Rabih Talhouk

Equipment Used:      Flowcytometer, X-Ray Film Developer, Fluorescence Microscope, and Gel Documentation System

 

Thesis Title:             The Role of Heterocellular Gap Junctional Communication in Mammary Epithelial Cell Differentiation

Graduate's Name:     Lina Abi Mosleh

Department:             Biology

Advisor's Name:      Dr. Rabih Talhouk

Equipment Used:     Flowcytometer, X-Ray Film Developer, Fluorescence Microscope, and Gel Documentation System.

 

October 2003

 

Thesis Title:              Regulation of COX-2 by Statins

Graduate's Name:     Ishraq Shamseddeen

Department:             Medical School

Advisor's Name:     Dr. Aida Habib

Equipment Used:     Gel Documentation System, and ELISA Reader

 

May 2004

 

Thesis title:                 Preliminary Evaluation of Two Lebanese Folk Medicinal plants for their Anti-Inflammatory Potentials

Graduate's Name:        Malak Esseily

Department:               Biology
Advisor:                     Rabih Talhouk
Equipment used :         xomat, centrifuge, Cell Culture facility

 

Thesis Title:             Role of Insulin and angiotensin II receptor subtype I antagonist on endothelin-I binding in diabetic rat hearts
 Graduate's Name:   Shehadeh Nehman Karam
 Department:            Human Morphology
 Advisor :  	Dr. Nuha Nuwayri-Salti
 Equipment used:      Fluorescence Microscope

 

 

 June 2004

 
Thesis Title:             Syntheses of 3,4-Substituted Cyclopentanols: Precursors to Carbocyclic Nucleoside Analogs
Graduate's Name: 	Niveen Nasser
 Department:            Chemistry
 Advisor:                  Dr. Kamal Bouhadir
 Equipment Used:     NMR spectrometer
 
 
Thesis Title:             Growth of Chromium Oxides By laser Ablation of Cr2O3 
 Graduate's Name:   	Samer Kahwagy.
 Department:            Physics
 Advisor:                  Dr. Malek Tabbal
 Equipment Used:    PLD, XRD, AFM
 
 

Thesis Title:              Assessment of Anemia, Iron, Folate, and Vitamin B12 Status in Lebanese Women of Childbearing Age                

Graduate's Name:    Lynn El Khatib

Department:            Nutrition   

Advisor:                  Dr. Nahla Hwalla

Equipment Used:     HPLC

 

Thesis Title:             Modification of Glucocorticoid Effects on Body Weight Gain and Plasma Lipids, By Changes in Diet Composition

Graduate's Name::   Annie Dekermenjian  

Department:           Nutrition

Advisor:                 Dr. Nahla Hwalla

Equipment Used:   Fluorescence Microscope

 

July 2004
 
Thesis Title:             Outdoor Chemistry of Carbonyls in the Coastal Atmosphere of Lebanon 
Graduate's Name:    Samar Moussa 

Department:             Chemistry
Advisor:                   Dr. Najat A. Saliba
Equipment used:      HPLC

 

Thesis Title:              Potential mechanisms of colon cancer prevention by thymoquinone extract  from black seed with an of it antioxidant

                                 activities

Graduate's Name:    Hiba Moukadem

 Department:            Biology
 Advisor:                  Dr. Hala Muhtasib
 Equipment used:      flowcytometer, Xomat
 

 August 2004

September 2004
 
Thesis Title:             Syntheses of Tosylhydrazone Derivatives of 3,4-Substituted Cyclopentanones
Graduate’s Name:    Bilal Abou Aleiwe
Department:      	Chemistry 
Advisor:   		Dr. Kamal Bouhadir       
Equipment Used:    	NMR spectrometer 

 

Thesis Title:             Rhythmicity,Composition and Geological Simulation in Front Propagation

                                Systems with Dissolution and Periodic Precipitation.
Graduate’s Name:    Maysam Al-Msharrafieh

Department:                Chemistry

Advisor:                      Dr Ribih Sultan    
Equipment used:         AAS

 

Thesis Title:             Amorphous to Crystalline Phase transition in Pulsed Laser Deposited Silicon Carbide
Graduate’s Name:    Aurore Said
Department:           Physics
Advisor:                 Dr. Malek Tabbal
Equipment Used:   PLD, XRD, AFM 

 

October 2004

 

Thesis Title:             The Way to Natural Bioactive Products in an endemic Lebanese Plant
Graduate's Name:    Saada Dakdouki
Department:            Chemistry
Advisor:                  Dr. Najat A. Saliba
Equipment  used:     HPLC, NMR
 
July
– August – September 2005

 

Thesis Title:

Antimicrobial Resistance of E.coli and Y. enterocolitica Isolated from Dairy Based Foods in Lebanon

Graduate’s Name:

Iman Saleh

Department:

Biology

Defense Date:

July 14th, 2005

Advisor:

Dr. Steve Harakeh

Equipment Used

PCR, Gel Documentation System

 

 

Thesis Title:

Evaluation of the Contamination Status and Antimicrobial Resistance of Staphylococcus and Salmonella Species Isolated from Dairy Based Products in Lebanon

Graduate’s Name:

Omar Nayef Zouhairi

Department:

Biology

Defense Date:

August 17th, 2005

Advisor:

Dr. Steve Harakeh

Equipment Used

PCR, Gel Documentation System

 

 

Thesis Title:

Isolation, Molecular Characterization and Antimicrobial Resistance of Brucella and Listeria Species in Representative Lebanese Foods

Graduate’s Name:

Nisreen Hassan Alwan

Department:

Biology

Defense Date:

September 29th, 2005

Advisor:

Dr. Steve Harakeh

Equipment Used

PCR, Gel Documentation System

 

 

Thesis Title:

Induction of Apoptosis by Epigallocatechin-3-Gallate (EGCG) in HTLV-1-Positive and – Negative Malignant T-Cells

Graduate’s Name:

Khalil Ahmad Abou El Ardat

Department:

Biology

Defense Date:

September 15th, 2005

Advisor:

Dr. Steve Harakeh

Equipment Used

Flowcytometer, XOMAT, Gel Documentation System

 

 

Thesis Title:

Mammary Epithelial Differentiation: The Role of Heterocellular Gap Junctional Intercellular Communication (GJIC) and Connexin Associated Proteins.

Graduate’s Name:

Rana Mroue

Department:

Biology

Defense Date:

July 1st, 2005

Advisor:

Dr. Rabih Talhouk

Equipment Used

XOMAT. Fluorescence Microscope, Flowcytometer, Centrifuge, Tissue Cell Culture Facility

 

 

Thesis Title:

Mammary Epithelial Cell Differentiation: A Role for Connexin 30

Graduate’s Name:

Maysa Mkalled

Department:

Biology

Defense Date:

July 1st, 2005

Advisor:

Dr. Rabih Talhouk

Equipment Used

XOMAT. Fluorescence Microscope, Flowcytometer, Centrifuge, Tissue Cell Culture Facility

 

 

Thesis Title:

Effect and Mechanism of Action of TNF-Alpha and PGE2 on Ion Transporters in Kidney and Liver Cells

Graduate’s Name:

Sara Riman

Department:

Biology

Defense Date:

August 5th, 2005

Advisor:

Dr. Sawsan Kreydiyyeh

Equipment Used

XOMAT, Gel Documentation System

 

 

Fall 2005-2006

 

 

Thesis Title:                       Differential Apoptosis by Galotanin in Human Colon Cancer Cells Distinct in their P53 Status: Potential

                                        Mechanisms Involved.

Graduate's Name:             Sahar Al Ayyoubi

Department:                      Biology

Advisor:                            Dr. Hala Muhtasib

Date:                                October 28th, 2005

Equipment Used :            Flowcytometer, Xomat, Real Time PCR

 

 

Thesis Title:                  Transport and Magnetic Properties of the New High Temperature Superconductors Tl2Ba2Ca2Cu(3 x)FexO10

                                    and Tl2Ba2Ca2Cu(3-x)ZnxO10

Graduate's Name:           Haybat Itani

Department:                   Physics

Advisor:                         Dr. Samih Isber

Date:                             November 18th, 2005

Equipment Used:           XRD, PPMS

 

 

Thesis Title:                   Mass Concentration and Inorganic Composition of Ambient Aerosols in Suburban Beirut

Subtitle:                        Implications Regarding Local Emissions and Long Range Transport

Graduate's Name:         Hovig Khoren Kouyoumdjian

Date:                             December 23rd, 2005

Advisor’s Name:           Dr. Najat Saliba

Department:                  Chemistry

Equipment Used:          Ion Chromatography, Flame and Furnace Atomic Absorption Spectrophotometry, Microwave Digestion.

 

Thesis Title:                 Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloro phenylquinoxaline 1,4-dioxide under oxic and hypoxic

                                   conditions: Potential Mechanisms Involved  

Graduate Name:             Wafica Sami Itani

Department:                 Biology

Advisor:                        Dr. Hala Muhtasib

Date:                             March 9, 2006

Equipment used:            XOMAT, flowcytometer, gel documentation system

 

June - July - September 2006

Thesis Title:                    Perinatal Hypoxia-Induced Apoptosis: New insights

Graduate Name:             Diana Jehad Azzam

Department:                   Biochemistry

Advisor:                        Dr. Mohammad Mikati

Date:                            September 2006

Equipment used :          HPLC

 

Thesis title:                  Identification and characterization of crude and purified extracts from the Indigenous Lebanese plant EP using                                    models of squamous cell carcinogenesis.    

Graduate Name:             Racha Halawi

Department:                 Biology
Advisor:                       Dr. Nadine Darwiche
Date of defense:           June 2006

Equipment used :          Flow Cytometer- Cell culture facility

 

Thesis title:                     Induction of Apoptosis by Ascorbic Acid in HTLV-1-Positive and –Negative Malignant T-cells.

Graduate Name:            Jihane khalife

Department:                   Biology
Advisor:                        Dr. Elias Baydoun
Date of defense:            September 2006

Equipment used:            Flow Cytometer, Spectrophotometer, Gel Documentation System, Cell Culture Facility.

 

 

January - February - March 2007

 

 

Thesis title:                    The Role of DNA damage Pathways in the Radiosentising Effects of 2-Benzoyl-6,7-dichloro-3-Phenylquinoxaline

                                    1,4-Dioxide

Graduate Name:            Joelle Michel Haykal

Department:                   Biology
Advisor:                         Dr. Hala Muhtasib
Date of defense:  
            February 28th, 2007

Equipment used :             Flowcytometer, Fluorescence Microscope, Gel Documentation System, Cell Culture Facility.

 

June - August - September 2007

 

Thesis Title:               Oil Spill Contaminants in Selected Vertebrates and Invertebrates of the Eastern Mediterranean Sea.

Graduate's Name:     Alia Sabra

Department:             Ecosystem Management

Advisor's Name:      Dr. Elie Barbour

Equipment Used:      Microwave Digestion

 

October - November - December 2007

 

Thesis Title:  The Role of Signal Transducer and Produer of Transcription 3 and Reactive Oxygen Species in Gallotanin – Induced Antiproliferation and Apoptosis in Human Colon Cancer.

Graduate's Name:     Widian Fouad Abi Saab

Department:             Biology

Advisor's Name:      Dr. Hala Muhtasib

Equipment Used:      Flowcytometer, XOMAT, Gel Documentation System

Date:                            October, 2007

 

April - May - June 2008

 

- Thesis Title:                      Synthesis of some Quinoxalines, Quinoxaline 1,4-dioxides, and Quinoxalinocinnoline N-oxide

- Student full name:             Mirna El-khatib
- Department:                     Chemistry
- Date of thesis:                 June 2008
- Advisor:                         Dr. Haddadin
- Instruments used at the CRSL: NMR and hplc-ms

 

- Thesis Title:                     The effect of dietary phosphorus manipulation on lipid status of rats 

                                        maintained on a high fructose diet.

- Student Full Name:         Lama E Mattar

- Department:                     Nutrition

- Advisor:                         Dr. Omar Obeid

- Date of thesis:                 June 2008

- Instruments used at the CRSL:  HPLC

 

 

- Thesis Title:                       The effect of Branched chain amino acids on meal patterns in rats

- Student Full Name:            Nabiha G Ramadan

- Department:                       Nutrition

- Advisor:                             Dr. Omar Obeid

- Date of Thesis :                  June 2008

- Instruments used at the CRSL: HPLC

 

- Thesis Title:                          The effect of exogenous connexin43 expression on mammary epithelial 

                                               tumor cell lines.

- Student Full Name:               Hashem A. Dbouk

- Department:                          Biology

- Date of Thesis:                        11-June-2008

- Advisor:                                  Dr Rabih Talhouk

- Instruments used at the CRSL: XOMAT, flowcytometer, and fluorescence microscope

 

- Thesis Title:                            Gap Junctions Mediate a STAT-5 Independent Beta-Casein Expression

- Student Full Name:                 Antoine Abboud Khalil

- Department:                           Biolgy

- Date of Thesis:                       12 June 2008

- Advisor:                                 Dr. Rabih Talhouk

- Instruments used at the CRSL: XOMAT

 

 

 

 
 
Publications
 
 
Article Title: 	Quinoxaline 1,4-dioxides induce G2/M cell cycle arrest and apoptosis in human colon cancer cells.
Author:		Gali-Muhtasib HU, Diab-Assaf M, Haddadin MJ. 
Department:	Biology
Magazine:		Cancer Chemother Pharmacol. 2005 Apr;55(4):369-78.
Equipment used : 	Flowcytometer
 

Article Title:         Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes
Author:                 Hala U. Gali-Muhtasib, Wassim G. Abou Kheir, Lynn A. Kheir, Nadine Darwiche and Peter A. Crooks

Department:          Biology
Magazine:             Anti-Cancer Drugs 2004, April, 15:389–399
Equipment Used:  Flow cytometer, fluorescence microscope

Article Title:         Quinoxaline 1,4-dioxides are Novel Angiogenesis Inhibitors that Potentiate Antitumor Effects of Ionizing Radiation. 
Author:                 Hala Gali-Muhtasib, Ph.D., Mazen Sidani, MSc., Fady Geara, M.D., PhD., Assaf-Diab Mona, Ph.D., Josianne Al-Hmaira, BSc.,                             Makhluf J. Haddadin, Ph.D., and Ghazi Zaatari, M.D.

Department:         Biology
Magazine:            International Journal of Oncology , 2004 May;24(5):1121-31.
Equipment Used: Flow cytometer, fluorescence microscope

 

Article Title:         Inhibition of proliferation and induction of apoptosis by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide in adult   T-cell leukemia cells.
Authors:             Steve Harakeh, Mona Diab-Assef, Marwan El-Sabban, Makhluf Haddadin, Hala Gali-Muhtasib

Department:         Biology
Magazine:             Chem Biol Interact. 2004 Jul 20;148(3):101-13.
Equipment Used: Flow cytometer, fluorescence microscope

 

Article Title:         Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-        dependent mechanism.
Author:                 Hala Gali-Muhtasib
Department:         Biology
Magazine:             International Journal of Oncology 2004 Oct;25(4):857-66.
Equipment Used: Flow cytometer, fluorescence microscope

 

Article Title:         Quinoxaline 1,4-dioxides INDUCE G2/M cell cycle arrest and apoptosis In human colon cancer cells.
Author:                 Hala U. Gali-Muhtasib Assaf-Diab Mona,  and Makhluf J. Haddadin

Department:         Biology
Magazine:             Cancer Chemotherpay and Pharmacology, in press
Equipment Used: Flow cytometer, fluorescence microscope

 

Article Title:           Exchange Coupling in Spins Quartet of Dimeric Polyoxoanions [M4(H2O)2(GeW9O34)2]12- (M = Mn2+, Cu2+)

Author:                 S. Isber, M. Tabbal, T. Christidis, S. Charar and F. Terki

Department:        Physics 
Magazine:           Journal of  Magnetism And Magnetic Materials (In Press)
Equipment used: Physical Properties Measurements System (PPMS), Spectrophotmeter UV, Visible and Near IF, X-Ray diffractometer.
 
 
 Article Title:           Crystal field investigations and magnetic properties of Nd3+ doped Bi4Si3O12
Author:                   S. Isber, M. Tabbal, T. Christidis, S. Charar, F. Terki and M. Ishii
Department:            Physics
Magazine:               Phys. Rev B. (In press)
Equipment used:      Physical Properties Measurements System (PPMS), Spectrophotmeter UV, Visible and Near IF, X-Ray diffractometer.
 
 
Article Title:            Cross talk between insulin and angiotensin II. Role of Lozartan in the prevention of cardiomaopathy in normotensive diabetic type I rats with no nephropathy
Author:                   Nuha Nuwayri-Salti M.D.
Department:            Human Morphology
Equipment Used:	Fluorescence Microscope 
 
 
Article Title:            N-(4-Hydroxyphenyl) Retinamide Induces Growth Arrest and Apoptosis in HTLV-I Transformed Cells. 
Authors:                  Darwiche, N., Hatoum, A.,  Dbaibo, G., Kadara, H., Nasr, N., Abou-Lteif, G., Bazzi, R., Hermine, O., de Thé, H. and Bazarbachi, A. 
Department:            Biology 
Equipment Used:     Flow cytometry 
Magazine:               Leukemia. 18: 607-615, 2004.
 
 
Article Title:            Stage-Specific Effect of N-(4-Hydroxyphenyl)Retinamide on Cell Growth in Squamous Cell Carcinogenesis. 
Authors:                  Kabbout, M., Hatoum, A., Abou-Lteif, G., Chakroun, I., Homaidan, F. and Darwiche, N.
Department:	Biology  
Magazine:               Molecular Carcinogenesis. 40: 12-23, 2004.
Equipment Used:     Flow cytometry, fluorescence microscopy, and dark room (develop X-ray fims)

  

 Article Title:            Crystal field investigations and magnetic properties of Nd3+ doped Bi4Si3O12Phys. 
Author:                   S. Isber, M. Tabbal, T. Christidis, S. Charar, F. Terki and M. Ishii
Department:            Physics
Magazine:                              Rev B71, 014405, pp1-5 (2005).
Date:                      November 2005
Equipment Used:     PPMS, XRD

 

Article Title: 	Apoptosis Induction by Epican Forte in HTLV-1 Positive and Negative Malignant T-Cells.
Authors:		S. Harakeh, M. Diab-Assaf, J. Khalifeh, K. Abu El-Ardat
Department:	Biology
Equipment Used:	Flowcytometer, Fluorescence Microscope, Gel Documentation System, and XOMAT.
 

Article Title:             Simulation of Geochmical banding in Acidization-Precipitation Experiments in Situ

Authors:                   Maysam Msharrafieh, Mazen El-Ghoul, Rabih Sultan

Department:             Chemistry

Equipment Used :     Atomic Absorption Spectrophotometer, Fluorescence Microscope, and X-Ray Diffractometer

 

 

Article Title:                Patterns with High Rhythmicity Levels in Multicomponent Liesegang Systems

Authors:                     Maysam Mshrrafieh and Rabih Sultan