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Former AUB Student Dr. Samir Hanash
Makes his Mark in New science |
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---The titles professor,
doctor, and researcher only begin to describe Samir Hanash, MD, a former
student at AUB. Starting out like other students of medicine, he pressed
further on to advanced research in a new field of science: proteomics.
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programs
in cells. Once the proteins are identified and analyzed, a variety of diseases
can be diagnosed and treated before becoming life threatening. Before researching proteomics, the study of an organism's proteins as a whole, and to better understand how they function individually, Dr. Hanash needed funding. Although he was turned down several times, he finally received the money he needed from the National Institute of Health. Later, in 1997, the National Cancer Institute gave the University of Michigan a five-year a award of $5.5 million for genetic study. ---Dr. Hanash and his colleagues. along with computer specialists, then worked on developing software for protein imaging analysis. They developed as well a two dimensional separation technology called IPG (Immobilized pH Gradients). Dr. Hanash and his team then used mass spectrometry to link protein separation with protein identification. ---At the Experimental Biology 2000 meeting in San Diego, California on April 18, 2000, Dr. Hanash presented data and information on a new protein separation method. The new technology, called liquid-phase protein separation, may help scientists separate cells into individual proteins. Previously, the technology could not detect most of the proteins made by each type of cancer, which is Dr. Hanash's main interest. In the liquid-phase protein separation, the proteins remain in liquid state during the separation process. In June 2001, Dr. Hanash was declared the inaugural president of the Human the human proteome." |
Proteome
Organization (HUPO). Formed in February 2001, HUPO was created to increase
awareness of the study of the Human Proteome Project. The purpose of the
project is to illustrate the importance of proteomics in diagnosis, prognosis,
and therapy of a disease, to encourage international cooperation, in order
to endorse further scientific research globally. ---In January 2002, at the Hilton Resort in San Diego, California, the Cambridge Healthtech Institute held a "Pep Talk" on proteomics. Protein expression, protein arrays, and the Human Proteome Project were all discussed. ---Dr. Hanash, the keynote speaker, began by defining the components of the Human Proteome Project. He described how different the genome and proteome are: while the genome is basically limited and one dimensional, the proteome has many dimensions. Furthermore, it changes according to the nature of and amounts of individual proteins, the location of the proteins, and the interactions between proteins. Any breakthrough, he added, is considered a step forward to "mine |
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